Paper on autoimmune lymphoproliferative syndrome (ALPS) published in Blood Advances

By Jake | June 22, 2017


Key Points:

  • FAS-dependent apoptosis in Vδ1 T cells makes the latter possible culprits for the lymphadenopathy observed in patients with FAS mutations.

  • Rapamycin and methylprednisolone resistance should prompt clinicians to look for Vδ1 T cell proliferation in ALPS-FAS patients.